Journal of Pathology and Translational Medicine

Sun A Kim

4 Articles

Chondroblastoma of the Lumbar Spine: A Case Report and Review of the Literature.: Sun A Kim, Kyung Ja Cho, Yong Koo Park, Jong Seok Lee, Heon Ju Kwon, Hyewon Chung, Mi Jung Kim; Korean J Pathol. 2011;45(5):532-536.; DOI: https://doi.org/10.4132/KoreanJPathol.2011.45.5.532

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We report a case of chondroblastoma arising in the lumbar spine in a 25-year-old man who presented with low back pain of 5 years duration. Plain radiography and computed tomography revealed a well-defined osteolytic mass surrounded by marginal sclerosis in the third lumbar vertebra. The mass encroached on the left neural foramen on magnetic resonance imaging. Histologically, the tumor consisted of round to oval cells with eosinophilic cytoplasm and randomly scattered osteoclastic type giant cells. There were characteristic chicken-wire calcification and aneurysmal bone cyst-like changes. Chondroblastomas of the lumbar spine are extremely rare, and only nine cases have been reported. Spinal chondroblastoma should be distinguished from other benign bone tumors, because it tends to show aggressive biological behavior with high recurrence and mortality rates.

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Chondroblastoma of Thoracic Vertebrae: a Case Report and Review of the Literature
Alireza Tabibkhooei, Parisa Javadnia
Indian Journal of Surgical Oncology.2024; 15(S1): 22. CrossRef
Clinicopathological characteristics and prognostic factors in axial chondroblastomas: a retrospective analysis of 61 cases and comparison with extra-axial chondroblastomas
Bo-Wen Zheng, Bo-Yv Zheng, Hua-Qing Niu, Ming-Xiang Zou, Hai-Lin Wu, Ming Wang, Xue-Lin Li
World Journal of Surgical Oncology.2023;[Epub] CrossRef
Commentary on Letter to the Editor concerning “Management of cranial chondroblastoma in adults; a pooled analysis” by Amr Muhammed et al.
Amr Muhammed
American Journal of Otolaryngology.2021; 42(1): 102749. CrossRef
Prognostic Significance of Tumor-Associated Macrophages in Chondroblastoma and Their Association with Response to Adjuvant Radiotherapy
Bo-Wen Zheng, Min-Liang Yang, Wei Huang, Bo-Yv Zheng, Tao-Lan Zhang, Jing Li, Guo-Hua Lv, Yi-Guo Yan, Ming-Xiang Zou
Journal of Inflammation Research.2021; Volume 14: 1991. CrossRef
Sacral chondroblastoma — a rare location, a rare pathology: A case report and review of literature
Bo-Wen Zheng, Hua-Qing Niu, Xiao-Bin Wang, Jing Li
World Journal of Clinical Cases.2021; 9(20): 5709. CrossRef
Intraoperative crush smear cytology of vertebral chondroblastoma: A diagnostic challenge
Shilpa P. Tathe, Sanjay N. Parate, Kirti N. Jaiswal, Archana A. Randale
Diagnostic Cytopathology.2018; 46(1): 79. CrossRef
Clinical features, treatments and long-term follow-up outcomes of spinal chondroblastoma: report of 13 clinical cases in a single center
Qi Jia, Chao Liu, Jian Yang, Yong Ji, Haifeng Wei, Tielong Liu, Xinghai Yang, Cheng Yang, Jianru Xiao
Journal of Neuro-Oncology.2018; 140(1): 99. CrossRef
Chondroblastoma of the thoracic spine: a rare location. Case report with radiologic-pathologic correlation
A. Venkatasamy, M. P. Chenard, G. Massard, J.-P. Steib, G. Bierry
Skeletal Radiology.2017; 46(3): 367. CrossRef

Adrenal Cortical Adenoma Developed in Adrenohepatic Fusion, a Mimicry of Hepatocellular Carcinoma: A Case Report.: Sun A Kim, Young Joo Lee, Kyoung Won Kim, Gyungyub Gong; Korean J Pathol. 2011;45(2):196-200.; DOI: https://doi.org/10.4132/KoreanJPathol.2011.45.2.196

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Abstract PDF

Adrenohepatic fusion is the union of the liver and adrenal gland with close intermingling of their respective parenchymal cells. Adrenal cortical adenoma arising in adrenohepatic fusion tissue is extremely rare, although adrenohepatic fusion itself is relatively common. Here we report a case of a 59-year-old man with a mass in the right lobe of his liver. The mass showed slight hyperattenuation during arterial phase and hypoattenuation during portal phase on dynamic computed tomography with contrast enhancement. On pathology, the mass consisted of round to polygonal cells with clear microvesicular or eosinophilic cytoplasm, arranged in nests or in a trabecular pattern. The tumor cells were positive for inhibin and melan-A, but negative for Hep Par-1. In the periphery of the mass, adrenohepatic fusion was identified between the liver and adrenal gland, and was simultaneously resected with the mass. We report this rare case, and discuss its clinical implications, especially the differential diagnosis with hepatocellular carcinoma.

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Adrenal cortical adenoma arising in an adreno-hepatic fusion: Case report and literature review of a potential diagnostic pitfall
Adam Stenman, Ivan Shabo, Jan Zedenius, C. Christofer Juhlin
Human Pathology Reports.2022; 29: 300656. CrossRef
Intrahepatic adrenocortical adenoma arising from adrenohepatic fusion mimicking hepatic malignancy
Yong Soo Cho, Jin Woong Kim, Hyun Ju Seon, Ju-Yeon Cho, Jun-Hee Park, Hyung Joong Kim, Yoo Duk Choi, Young Hoe Hur
Medicine.2019; 98(23): e15901. CrossRef
Direct and indirect imaging features of adrenohepatic fusion
Jung Jae Park, Byung Kwan Park, Chan Kyo Kim
Abdominal Radiology.2016; 41(2): 377. CrossRef

Solitary Fibrous Tumor of the Kidney: A Report of Two Cases with Review of Literature.: Sun A Kim, Jung Eun Hwang, Jae Y Ro, Kyung Ja Cho, Cheryn Song, Mi Jung Kim; Korean J Pathol. 2010;44(4):420-425.; DOI: https://doi.org/10.4132/KoreanJPathol.2010.44.4.420

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Abstract PDF

Solitary fibrous tumor (SFT) is a benign mesenchymal neoplasm usually occurring in the pleura. Kidney is one of the rarest sites for SFT. We report here on two cases of renal SFT found in 30-year-old and 33-year-old men with review of the literatures. Both cases manifested as well-enhanced solid masses in kidney and radical nephrectomies were done. The tumors consisted of bland-looking spindle cells arranged in short, ill-defined fascicles and storiform pattern with characteristic hemangiopericytoma-like blood vessels. The tumor cells were strongly positive for CD34 and CD99, focally positive for bcl-2, and negative for cytokeratin and human melanoma black-45 on immunohistochemical stainings. Possibility of SFT should be considered in the differential diagnosis of a renal mass which consists of benign-looking spindle cells and hemangiopericytomatous blood vessels. Immunohistochemical staining for CD34 is essential to confirm the renal solitary fibrous tumor.

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Solitary fibrous tumor located in the sella turcica: A report of two cases and review of the literature
XIAO YANG, QINGJUN JIANG, BINGBING YU
Oncology Letters.2015; 10(1): 354. CrossRef
Pediatric Renal Solitary Fibrous Tumor
William W. Wu, Julia T. Chu, Stephen G. Romansky, Lisa Shane
International Journal of Surgical Pathology.2015; 23(1): 34. CrossRef

Clinical Outcome of Surgically Resected Pancreatic Intraductal Papillary Mucinous Neoplasm According to the Marginal Status: A Single Center Experience.: Sun A Kim, Eunsil Yu, Song Cheol Kim, Jihun Kim; Korean J Pathol. 2010;44(4):410-419.; DOI: https://doi.org/10.4132/KoreanJPathol.2010.44.4.410

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Abstract PDF

BACKGROUND
Surgical resection is the treatment of choice of intraductal papillary mucinous neoplasm (IPMN) of the pancreas. However, the benefit of clearing resection margin is still controversial.
METHODS
We reviewed 281 surgically resected cases of IPMN. The recurrences were compared according to the histologic grade (benign or borderline IPMN, malignant noninvasive IPMN, invasive carcinoma) and size (pancreatic intraepithelial neoplasia, PanIN, less than 0.5 cm in the long axis; and IPMN, greater than or equal to 0.5 cm) of the residual lesions at the resection margin.
RESULTS
Sixty cases (21.4%) were invasive carcinoma, and 221 (78.6%) noninvasive cases included 87 (31.0%) benign, 107 (38.1%) borderline and 11 (3.9%) malignant noninvasive IPMN cases. In noninvasive IPMN, increased recurrence in patients with five or more years of follow-up was only related to the involvement of resection margin by severe dysplasia. The recurrence of invasive carcinoma was high (27.3%) even when the resection margin was clear, and was not related to the grade or size of residual tumors at the resection margin.
CONCLUSIONS
Invasiveness is a strong risk factor for recurrence in IPMN regardless of the status of the resection margin. However, in noninvasive IPMN, histologic grading of residual lesions at the resection margin predicts local recurrence.

Citations

Citations to this article as recorded by

Systematic review of challenging issues in pathology of intraductal papillary mucinous neoplasms
Laura D. Wood, N. Volkan Adsay, Olca Basturk, Lodewijk A.A. Brosens, Noriyoshi Fukushima, Seung-Mo Hong, Sung-Joo Kim, Jae W. Lee, Claudio Luchini, Michaël Noë, Martha B. Pitman, Aldo Scarpa, Aatur D. Singhi, Mariko Tanaka, Toru Furukawa
Pancreatology.2023; 23(7): 878. CrossRef
The Use of Intraoperative Frozen Sections in Guiding the Extent of Pancreatic Resections for Intraductal Papillary Mucinous Neoplasms
Zhikai Chi, Deepti Dhall, Richard Mertens
Pancreas.2022; 51(1): 63. CrossRef
Recurrence of non-invasive intraductal papillary municious neoplasm seven years following total pancreatectomy
Nayima M. Clermont Dejean, Sinziana Dumitra, Jeffrey S. Barkun
International Journal of Surgery Case Reports.2013; 4(9): 789. CrossRef

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